Traditional submerged cell culture techniques have well-known limitations for aerosol exposure studies; for instance, the impact of exposure dilution within the media and the poor solubility/sedimentation of some exposure particles1. Air liquid interface (ALI) cultures are a technique whereby cells are grown on a microporous membrane insert, immersed in a media-containing well.
inExpose Featured in recent nature publication Congratulations to Dr. Blackwell’s team at Vanderbilt University who recently published in Nature Communications1 with the inExpose! As you may
FlexiVent – Used in Recent Pulmonary Fibrosis Research Pulmonary fibrosis describes a condition in which the normal lung anatomy is replaced by a process of
Function follows form and form follows function The flexiVent makes assessing mechanical properties of the lung a relatively simple undertaking. However, understanding the underlying physiological processes and
To Open or Close the Lungs – That Is the Question! Although often necessary, mechanical ventilation of small animals during pulmonary measurements can lead to
Longitudinal Studies With the flexiVent to Acquire Lung Mechanics When developing an appropriate protocol to assess respiratory mechanics, there is a trade-off between accuracy of
Empower Yourself Attending a training such as the Phenotyping Mice Models of Human Lung Disease organized by the Jackson Laboratory is a great way to advance skillsets
E-cigarette vapour deposition E-cigarette vapour composition is influenced by a number of factors. Some of which relate to the device physically (battery charge, wattage/temperature control,
Pulmonary Hypertension Animal Models A lack of validated pulmonary hypertension animal models is the reason why there aren’t enough studies exploring the pathophysiology and therapies
Reproducible E-cigarettes Exposure Environments Studies addressing the potential risks associated with electronic cigarette (e-cig) usage are urgently needed, given their rising use and popularity, especially
Alpha-1 Antitrypsin (AAT) Deficiency Alpha-1 antitrypsin (AAT) deficiency is an inherited disorder, most prevalent in populations of European ancestry, and is underdiagnosed. It results from
Whole Body Plethysmograph – vivoFlow Launches at EB 2019 SCIREQ is preparing for the upcoming Experimental Biology Meeting that will take place in Orlando from April 6-9,
Circadian Rhythm Effects Lung Function Circadian rhythm changes can affect lung function, introducing susceptibility to infection and other adverse effects on health and disease.
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