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Plethysmograph

vivoFlow+ whole body, head out
& double chambers

Plethysmography is a standard method for studying pulmonary function in conscious, spontaneously breathing laboratory subjects. The barometric plethysmography technique measures flow and pressure changes that occur while the subject is breathing, before and after exposure to a drug or other challenges. It is easily adapted to various subject sizes and species, and is often used for longitudinal studies where the subjects are studied for multiple hours on successive experiment days.

 
Compatible Animals
Mouse
Rat
Hamster
Non-Human Primate
Research Applications & Use Cases
Techniques & Measurements
Features & Benefits
Conscious & Spontaneously Breathing
Ease of Use
Efficient Screening
IOX2 software for data acquisition & real-time analysis

IOX2 Software is a GLP-compliant solution designed for researchers to efficiently acquire, analyze, view, and store physiological data generated during preclinical experiments. With a powerful suite of analysis tools, IOX2 provides comprehensive real-time signal processing to ensure precise and reliable results.

  • Real-time analysis and ambulatory monitoring.
  • Flexible tuning analyzers for breath acceptance or rejection (e.g.: rejection ranges can be set for any or all parameters: TV, f, MV, PIF, PEF, etc.).
  • Automated alarms and email alerts for relevant physiologic triggers.
  • Easily configurable trends, data tables, and signal graphs to display detailed information for single or multiple subjects.
  • Replay or review data files.
  • High Definition video signals synchronized with respiratory waveforms.
  • Protocols to automate user workflow and act as experimental guidelines.
  • Apnea and cough detection.
  • Respiratory flow (RF) analyzer for ventilatory parameters.
  • Dual-chamber respiratory flow (DCRF) analyzer for specific airway resistance.
  • Multiple independent physiologic channels can be captured simultaneously for high throughput.
  • Links to emka TECHNOLOGIES and DSI telemetry.
Configurations & Extensions
Specifications Mouse vivoFlow+ Rat & Guinea-Pig vivoFlow+
Internal diameter 80 mm 200 mm
Height 87 mm 100 mm
Volume 0.44 L 3.14 L
Animal weight range >10 g 250-560 g

Resources

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