Experts at the forefront of inhalation toxicology research discuss pre-clinical models of smoke exposure and provide deeper analysis of the cardiopulmonary outcomes.
Watch now for a full insight into considerations surrounding pre-clinical exposure models such as acute vs chronic exposures, nose-only vs whole body, physiological subject assessment and smoke particulate specifications.
The flexiVent is widely regarded as the gold standard for in vivo lung function measurements. It goes beyond traditional resistance and compliance measurements, and captures crucial details about the mechanical properties of conducting airways, terminal airways and parenchyma.
The flexiVent achieves the highest sensitivity and reproducibility by precisely controlling experimental conditions.
The inExpose is designed to operate under a standard fume hood, and distinguishes itself by its compact size and high level of integration. Its modularity and integration permits both nose-only and/or whole body exposure of rodents, as well as automated generation of cigarette smoke and aerosols. The small form factor reduces direct and indirect costs, and low internal volumes also minimize unintended dilution of precious compounds.
Plethysmography is a standard method for studying pulmonary function in conscious, spontaneously breathing laboratory subjects. The barometric plethysmography technique measures flow and pressure changes that occur while the subject is breathing, before and after exposure to a drug or other challenges. It is easily adapted to various subject sizes and species, and is often used for longitudinal studies where the subjects are studied for multiple hours on successive experiment days.
The Fraunhofer Institute for Toxicology and Experimental Medicine ITEM and SCIREQ Scientific Respiratory Equipment Inc. are pleased to announce their collaboration for the development and commercialization of the ExpoCube® platform. The ExpoCube® is a precision aerosol exposure system for pulmonary research. It permits highly accurate and reproducible deposition of particles from inhalable aerosols onto cells and tissues from the lungs.
Dr. Wold studies the effects of E-cigarettes use on the cardiovascular system, & the effects of dust from the collapsed World Trade center on first responders in a preclinical model. Learn more about his research in this interview!
The Krymskaya lab focuses on preclinical and translational research in rare and common lung diseases from pulmonary LAM to asthma. Learn more about her work and get her thoughts on the current state of preclinical rare lung disease research.
The Halayko lab focuses on the
pathogenesis of bronchial asthma and is at the forefront of preclinical asthma research. We sat down with Dr. Halayko to learn more about his work and get his thoughts on the current state and future of asthma research.
Dr. Vanoirbeek is a research Associate Professor at KU Leuven. His interests are occupational and environmental exposure assessment and toxicology, with a special focus on experimental lung immune toxicology. Learn more about his work in this interview!
Dr. Davis is a PI in the Department of Veterinary Biosciences at The Ohio State University. Research in the Davis lab is focused on the pathophysiologic effects of pulmonary viral infections. Learn more about his work in this interview!
Dr. Carolyn Baglole is an Associate Professor in the Department of Medicine at McGill University. Her laboratory focuses on how chronic lung diseases such as COPD are associated with environmental exposures, particularly cigarette smoke.
Welcome to SCIREQ’s knowledge center. You can find everything from software registration to document downloads to complete list of SCIREQ publications in this section. Everything you need to get the most out of your SCIREQ system.