Obesity is a significant contributor to respiratory disorders such as Obesity Hypoventilation Syndrome (OHS) and sleep apnea, both of which are characterized by reduced respiratory chemosensitivity. These conditions not...
Rett syndrome (RTT) is a severe neurodevelopmental disorder caused by mutations in the MECP2 gene, leading to various symptoms, including cognitive impairment, motor dysfunction, and significant respiratory abnormalities.
Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterized by progressive scarring of the lungs, which severely impairs lung function over time.
Sudden Unexpected Death in Epilepsy (SUDEP) remains a critical concern in epilepsy management, with the underlying mechanisms still not fully understood.
Despite international treaties, the usage of chemical weapons is still a concern nowadays. This article highlights a study using Dual-chamber plethysmography for the determination of the NOAEL dose of...
Pulmonary fibrosis, particularly idiopathic pulmonary fibrosis (IPF), represents a significant challenge in healthcare due to its detrimental impact on lung function and limited treatment options.
In this blog, we will explore the groundbreaking preclinical work on CSX-1004, a fully human monoclonal antibody with exceptional affinity for fentanyl and related analogs, offering hope in the...
In the intricate web of neural circuits that guide our every move, a recent study has shed light on a fascinating phenomenon: the arrest of ongoing movements
Combining implantable telemetry with whole body plethysmography offers a powerful approach that provides researchers with an in-depth understanding of respiratory patterns and mechanisms.
Opioid-related addiction, overdose and death is a widespread public health crisis. A recent paper provides a model example of the how plethysmography can be used to assess ventilatory behavior...
The ability to time intervals is critical for fundamental animal behaviors such as anticipating rewarding or aversive events. However, the neurobiological basis of interval timing in Pavlovian associative learning...
Exercising outdoors, particularly when done at high intensity and in polluted environments, could cause molecular alterations that could impact pulmonary function.
Our legacy plethysmograph system has officially retired starting September 1, 2019. Over the past few years it has become increasingly difficult to support our legacy plethysmography data acquisition hardware and...
The airways contribute to the total compliance of the respiratory system and, over the last 50 years or so, researchers have had an interest in establishing their specific contribution...
At this year’s annual meeting, SCIREQ focused our discussions around our plethysmography system – the vivoFlow – which permits a continuous, non-invasive assessment of breathing patterns in conscious subjects,...
SCIREQ recently attended this year’s Society of Toxicology (SOT 2022) Annual Meeting and ToxExpo. A common topic was in vitro exposure with air pollutants or wood fire smoke exposure....
