Resources

Build on your knowledge of various topics in pre-clinical pulmonary research including animal models used in pulmonary research studies, study design, grant justifications and more.

 

In the world of respiratory research, the choice of mouse strain can make or break the success of an experimental disease model. Recent findings shed light on the importance of selecting the appropriate strain by elucidating key differences in lung mechanics between two commonly used strains: C57BL/6 and BALB/c mice.

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Respiratory Function in Preclinical Models of Alpha-1 Antitrypsin Deficiency flexiVent System for Respiratory Mechanics and Airflow Measurements for Ferrets Alpha-1 Antitrypsin Deficiency (AATD) is a

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Complementing Plethysmography Pulmonary Function with Detailed Respiratory Mechanics Measurements Plethysmography is a proven method to study pulmonary function in conscious, spontaneously breathing subjects. Given its

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Plethysmography Techniques & Respiratory Science: A crucial tool in the study of opioid abuse and breathing pathologies Erica Levitt, PhD, from the University of Florida,

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Ventilator-Assisted Aerosol Delivery (VAAD) VAAD is a new innovative technique using the flexiVent, introduced to improve in vivo aerosol administrations for drug delivery and disease

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E-cigarettes Induce Cardiac Arrhythmia and Conduction Defects in Mice In recent years, electronic cigarettes have become rapidly popular worldwide, despite growing evidence that they adversely

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In our recent panel discussion event, we explored the considerations for performing inhalation exposure studies with cigarettes, e-cigarettes, and cannabis.

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E-cigarette Profiles Used With the inExpose » The inExpose can be configured to generate e-cigarette smoke to fit a wide range of applications and budgets.

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Referencing SCIREQ Systems »  Referencing the flexiVent flexiVent FX, SCIREQ Scientific Respiratory Equipment Inc., Montréal, Canada flexiVent FX with NPFE extension, SCIREQ Scientific Respiratory Equipment

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Recommended Parameters Per Disease »  The flexiVent is an integrated platform for pre-clinical pulmonary research and offers comprehensive parametrized assessments of lung function. Each set

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IACUC Considerations »  Animal models are crucial to preclinical respiratory research as they help in improving the understanding of disease pathways and assessing potential therapies.

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Bronchoalveolar Lavage Protocol » The flexiVent goes beyond traditional resistance and compliance measurements, and captures crucial details about the mechanical properties of conducting airways, terminal airways

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23 Things You Should Include in Your Lab Handbook » Created in collaboration with Samuel Mehr from The Music Lab at Harvard, this is the ultimate guide

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The flexiVent & COPD » How can the flexiVent advance your COPD research? The flexiVent is a comprehensive tool allowing an integrated assessment of various

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flexiVent Methods & Protocol »  The flexiVent goes beyond traditional resistance and compliance measurements, and captures crucial details about the mechanical properties of conducting airways,

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The flexiVent & Asthma » How can the flexiVent advance your asthma research? The flexiVent goes beyond traditional resistance and compliance measurements, and captures crucial

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Understanding Respiratory Physiology » Why does air move in and out of the lungs with every breath? This is a question frequently asked by non-physiologists

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The flexiVent & COVID-19 »  The flexiVent is an advanced pulmonary research platform highly adapted to assist in COVID-19 preclinical experimentation. The flexiVent measures detailed

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Anesthesia Regimes for flexiVent Studies »  flexiVent experiments provide lung function outcomes with a high degree of sensitivity and reproducibility using even small subject groups. This

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New Mouse Handling Recommendations For Improving Animal and Handler Wellbeing »  Preclinical models are invaluable to the importance of pulmonary research. Animal models bridge the

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The flexiVent & ARDS »  How can the flexiVent advance your ARDS research?  The flexiVent is a highly programmable computer-controlled piston ventilator as well as

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Moving into In Vivo Research »  While working with in vivo models can be challenging, even intimidating, SCIREQ strives to make in vivo lung function measurements accessible

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Translational Pre-Clinical Models of COVID-19   » Panel Discussion Recording   SCIREQ hosted a virtual panel discussion with leading preclinical infectious disease researchers focusing on Preclinical

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Grant Justifications for Equipment »  Grant justifications may be requested by your funder. These documents explain the purpose of each item in the budget and

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The flexiVent & Fibrosis »  How can the flexiVent advance your pulmonary fibrosis research? The flexiVent’s ability to synchronize with micro-CT scanners, provide static and

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COPD Animal Models » COPD (Chronic Obstructive Pulmonary Disease) is a disease state characterized by significant airflow limitation and lung tissue destruction. The main cause

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Animal Models of Asthma » Asthma has reached epidemic proportions worldwide and typically starts early in life. It is a complex disease that can be

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Small Animal Models Of Pulmonary Fibrosis »  Pulmonary fibrosis (interstitial lung fibrosis) has a varied etiology; including inflammatory diseases and injury, aging, environmental exposures (e.g. asbestos,

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