FlexiVent Resources

Airway Hyperreactivity in Chlorine Exposed EIB Swimmers Model

Airway hyperresponsiveness (AHR) and exercise-induced bronchoconstriction (EIB) are conditions commonly affecting high-intensity athletes such as competitive swimmers.AHR and EIB in athletes have been well defined, however, studies focusing on...

Advantages of ALI Exposure – expoCube

Traditional submerged cell culture techniques have well-known limitations for aerosol exposure studies; for instance, the impact of exposure dilution within the media and the poor solubility/sedimentation of some exposure...

Tissue Baths in Respiratory Disease Models

Isolated tissue baths, also known as organ chambers, are tools that have been used in the discipline of pharmacology for over 150 years to evaluate tissues contractility and relaxation...

Pulmonary Vascular Remodeling

Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disorder of the lungs that has been a major public health problem, and has been the third leading cause of...

Oscillometry In the Drug Development Process

The current COVID-19 pandemic has highlighted the need for a rapid development of therapeutic approaches to treat respiratory diseases. Yet, respiratory therapeutic candidates have until now displayed a...

Mucolytic Treatment in Allergic Airway Disease

Asthma is a complex disease, whose principal characteristics include reversible airflow obstruction, airway hyperresponsiveness (AHR), airway inflammation, airway remodeling and mucus hypersecretion. Airway mucus hypersecretion specifically is an important...

Longitudinal Studies with SCIREQ Systems

Longitudinal studies offer a wealth of information, particularly for diseases progression or development studies. In addition, smaller sample sizes are possible to accumulate significant data, as subject assessment is...

Animal Models for Pulmonary Diseases

Animal models are crucial in advancing our knowledge and understanding of pulmonary diseases. Using alternatives models, such as computer simulations, is simply not advanced enough to elucidate all the...

Work of Breathing & Airway Compliance

Work of Breathing & Airway Compliance The latest release of flexiWare (8.2) brings with it the capacity to assess both work of breathing (WOB) and airway compliance, expanding the...