Respiration & Neural Dynamics in Odor Fear Learning
The ability to time intervals is critical for fundamental animal behaviors such as anticipating rewarding or aversive events. However, the neurobiological basis of interval timing in Pavlovian associative learning is poorly understood.
Pulmonary Impacts of Exercise in Polluted Environments
Exercising outdoors, particularly when done at high intensity and in polluted environments, could cause molecular alterations that could impact pulmonary function.
Ending Support for Legacy Plethysmography
Our legacy plethysmograph system has officially retired starting September 1, 2019.
Over the past few years it has become increasingly difficult to support our legacy plethysmography data acquisition hardware and software, with considerable rises in costs associated with maintenance and support for existing systems. After careful consideration, it was decided to retire the legacy plethysmograph system.
Assessing the Airway Contribution To Total Respiratory Compliance
The airways contribute to the total compliance of the respiratory system and, over the last 50 years or so, researchers have had an interest in establishing their specific contribution Indeed, the airway diameter as well as the volume of air available for ventilation following inspiration can both be affected by a change in the distensibility of the airways.
Experimental Biology 2022
At this year’s annual meeting, SCIREQ focused our discussions around our plethysmography system – the vivoFlow – which permits a continuous, non-invasive assessment of breathing patterns in conscious subjects, and allows for automated exposure to gas challenges, as well as aerosol delivery, wired and vascular access.
SCIREQ at Society of Toxicology 2022
SCIREQ recently attended this year’s Society of Toxicology (SOT 2022) Annual Meeting and ToxExpo. A common topic was in vitro exposure with air pollutants or wood fire smoke exposure. In addition to the posters, here are some of the highlights from this year’s SCIREQ booth!
Chronic Intermittent Hypoxia and Hypertension
Obstructive sleep apnea syndrome (OSA) is a complete or partial airway obstruction that can cause significant physiological disturbances with various clinical impacts such as snoring, nocturnal awakening, or daytime sleepiness.
Longitudinal Studies with SCIREQ Systems
Longitudinal studies offer a wealth of information, particularly for diseases progression or development studies. In addition, smaller sample sizes are possible to accumulate significant data, as subject assessment is possible at multiple time points.
Animal Models for Pulmonary Diseases
Animal models are crucial in advancing our knowledge and understanding of pulmonary diseases. Using alternatives models, such as computer simulations, is simply not advanced enough to elucidate all the biological mechanisms inside a living creature.
vivoFlow for Preclinical SARS-CoV-2 Hamster Studies
As in humans, the Angiotensin I Converting Enzyme 2 (ACE2) receptors of hamsters naturally permit binding of the SARS-CoV-2 virus spike protein. This suggests that hamsters are an important