The recent publication by Noël et al. entitled Generation of Electronic Cigarette Aerosol by a Third-Generation Machine-Vaping Device: Application to Toxicological Studies, is a noteworthy example to accelerate and harmonize e-cig research findings through the use of reproducible exposure environments.
Effects of short‐term electronic (e)‐cigarette aerosol exposure in the mouse larynx. (2024). Easwaran, M., et al. Laryngoscope, 134(3): 1316-1326
Vaping-Dependent Pulmonary Inflammation Is Ca2+ Mediated and Potentially Sex Specific. (2024). Shipman, J.G., et al. International Journal of Molecular Sciences, 25(3), 1785
Increased oxidative stress responses in murine macrophages exposed at the air-liquid interface to third- and fourth-generation electronic nicotine delivery system (ENDS) aerosols. (2023). Pinkston, R., et al. Toxicology Reports, 11, 40-57
Sex-Specific Alterations of the Lung Transcriptome at Birth in Mouse Offspring Prenatally Exposed to Vanilla-Flavored E-Cigarette Aerosols and Enhanced Susceptibility to Asthma. (2023). Noel, A., et al. Int. Journal. Environ. Res. Public Health 20(4), 3710
E-cigarette exposure causes early pro-atherogenic changes in an inducible murine model of atherosclerosis. (2023). Alakhtar, B., et al. Frontiers Toxicology, 5, 1244596
Chronic low-level JUUL aerosol exposure causes pulmonary immunologic, transcriptomic, and proteomic changes. (2023). Been, T., et al. FASEB Journal, 37(2): e22732
Pulmonary immune response regulation, genotoxicity, and metabolic reprogramming by menthol- and tobacco-flavored e-cigarette exposures in mice. (2023). Muthumalage, T., et al. Toxicological Sciences, 193(2): 146-165
Multi-omic assessment shows dysregulation of pulmonary and systemic immunity to e-cigarette exposure. (2023). Sciesza, D.P., et al. Respiratory Research, 138(24)
Switching from tobacco cigarettes in very early pregnancy: The effects of in utero e-cigarette exposure on mouse offspring neurodevelopment and behaviour. (2023). Bakker, C., et al. Physiology & Behavior, 263, 114118
Rat bronchoalveolar lavage proteome changes following e-cigarette aerosol exposures. (2023). Day, N.J., et al. Lung Cellular and Molecular Physiology, 324(5): 571-583
Effects of Electronic (E)-cigarette Vapor and Cigarette Smoke in Cultured Vocal Fold Fibroblasts. (2022). Martinez, J., et al. Laryngoscope, 133(1): 139-146
E-cigarette exposure augments murine abdominal aortic aneurysm development: role of Chil1. (2022). Mulorz, J., et al. Cardiovascular Research, 119(3): 867-878
Maternal electronic cigarette use during pregnancy affects long-term arterial function in offspring. (2022). Aboaziza, E., et al. Journal of Applied Physiology, 134(1): 59-71
Dr. Wold’s lab studies the effects of Alzheimer’s disease on cardiac function, the effects of e-cigarette usage on the cardiovascular system, and the cardiac effects of dust from the collapsed World Trade Center on first responders in a preclinical model. Learn more about his research and get his thoughts on the current state and future of inhalation toxicology research in this interview.
In this on demand panel discussion, experts at the forefront of inhalation toxicology research delve into the topic of Pre-Clinical Models of Smoke Exposure. Drs. Alex Carll, Laura Crotty Alexander, Carolyn Baglole, and Alexandra Noël will provide deeper analysis of pre-clinical smoke modelling and the cardiopulmonary outcomes.
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