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E-cigarettes Induce Cardiac Arrhythmia and Conduction Defects in Mice

In recent years, electronic cigarettes have become rapidly popular worldwide, despite growing evidence that they adversely impact cardiopulmonary health. Further scientific evidence is needed to clarify the risks of e-cigarettes and guide the use and regulation of these nicotine aerosol delivery devices. The rapid adoption of e-cigarettes, especially amongst youth, has spurred a rush to elucidate the health implications of the inhalation of their aerosols.

A recent study by Dr. Carll et al. has uncovered direct cardiovascular consequences such as the induction of spontaneous cardiac arrhythmias, changes in cardiac conduction properties, and autonomic reflexes in a mouse model of e-cigarette exposure. This series of work monitors real time cardiovascular electrophysiology during and after acute exposure sessions to e-cigarette aerosols or combustible cigarette smoke.

This document provides a summary of this study by Dr. Carll et al. at the University of Louisville published in Nature Communications.