Cardiopulmonary Impact of Wildfire Smoke

As global temperatures rise, wildfires are increasingly recognized as major public health crises. Exposure to wildfire smoke is known to worsen respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD).

Could a Novel BET Inhibitor Protect the Lungs from Secondhand Smoke?

Nearly half of the U.S. population remains at risk from the silent threat of secondhand smoke. Chronic exposure to triggers a cascade of inflammation and vascular damage that can lead to irreversible conditions like COPD and emphysema.

Cold Air and Pollution: A Combined Challenge for the Airways

Exercise-induced bronchoconstriction (EIB) is a hallmark of asthma and other respiratory diseases. It occurs when vigorous physical activity triggers transient and reversible airway narrowing. Environmental factors such as cold, dry air and air pollution are known to exacerbate symptoms, particularly in athletes and individuals exercising in urban environments.

joVE – In vitro Cannabis Exposures of Lung Epithelial Cells

Cannabis is used by an estimated 192 million people around the world. Most people use cannabis through the inhalation of cannabis smoke, which contains combustion by-products that can negatively affect lung health. . There is currently no standardized in vitro model for assessing the effects of dry cannabis vapor.

Comparative Analysis of Combustible and Electronic Cigarette Exposure

While combustible cigarette smoke (CCS) is a well-established carcinogen, the oncogenic potential of electronic cigarette vapor (ECV) remains underexplored. A recent study led by Dr. Moghaddam et al. at The University of Texas MD Anderson Cancer Center provides a rigorous comparative analysis of CCS and ECV exposure in a KRAS-mutant lung adenocarcinoma (KM-LUAD) mouse model.

The Impact of Cannabis Vapor on the Lungs and What We Learn from the Right Model

As cannabis use increases, so does the availability of products marketed as safe alternatives to smoking. One of these products is the dry herb vaporizer, which heats the cannabis flower without burning it. This process releases cannabinoids for inhalation. But how safe are these products?

Exploring ALI Exposures: From Cell Lines to Endpoints

Traditional submerged cell culture techniques have well-known limitations for aerosol exposure studies; for instance, the impact of exposure dilution within the media and the poor solubility/sedimentation of some exposure particles1. Air liquid interface (ALI) cultures are a technique whereby cells are grown on a microporous membrane insert, immersed in a media-containing well.

Preclinical Neonate Research

Preclinical Neonate Research Preclinical Pediatrics and Neonate Research Pediatrics and neonatology involves learning more about development and growth through the first stages of life. Early lung development studies investigate the some of the most vulnerable stages of life and must overcome significant experimental challenges when working with small, fragile and uncooperative subjects. The research targets a […]

The Relationship Between e-Cigarette Exposure, Sex Steroids, and COVID-19

Throughout the global COVID-19 pandemic, there has been a noticeably higher mortality rate in males compared to females. Though the mechanism that causes this remains unknown, Dr. Sharma and Dr. Zeki hypothesize

Insights From SRNT 2021

SCIREQ recently attended this year’s Society For Research On Nicotine and Tobacco (SRNT 2021) Annual Meeting!