Providing Detailed Insight Into Lung Inflammatory Responses

The emergence of novel zoonotic outbreaks such as COVID-19 continue to result in high mortality rates, as seen in previous epidemics (i.e SARS & MERS).

Animal Models of Rett Syndrome

Rett syndrome is a severe neurodevelopmental disease resulting from a loss of function mutation in MeCP2; an epigenetic modulator of transcription regulation

Reproducible e-Cigarettes Exposure Environments

Reproducible E-cigarettes Exposure Environments Studies addressing the potential risks associated with electronic cigarette (e-cig) usage are urgently needed, given their rising use and popularity, especially in youth.  Coordinated efforts are required to tackle the challenge of addressing key scientific questions, as there is a diversity of devices and e-liquid formulations that exists, as well as […]

Alpha-1 Antitrypsin (AAT) Deficiency

Alpha-1 Antitrypsin (AAT) Deficiency Alpha-1 antitrypsin (AAT) deficiency is an inherited disorder, most prevalent in populations of European ancestry, and is underdiagnosed. It results from mutations in the SERPINA1 gene, leading to either a reduced level or function of the AAT protein. AAT deficiency results a variety of health issues, particularly predisposition to the development of liver […]

Whole Body Plethysmograph – vivoFlow launches at EB 2019

Whole Body Plethysmograph – vivoFlow Launches at EB 2019 SCIREQ is preparing for the upcoming Experimental Biology Meeting that will take place in Orlando from April 6-9, 2019. At this meeting we launch our latest development: the vivoFlow – WBP (Whole Body Plethysmograph Chamber). The vivoFlow is fully compatible with our current system and has several design features which both […]

Circadian Rhythm Effects Lung Function

Circadian Rhythm Effects Lung Function Circadian rhythm changes can affect lung function, introducing susceptibility to infection and other adverse effects on health and disease. What does the circadian rhythm do? The circadian rhythm regulates many physiological parameters including lung function, immune responses, and cardiopulmonary function. The master circadian pacemaker is located in the anterior of […]