Understanding the Pulmonary Effects of Inhaled Arsenic Trioxide (ATO)

Arsenic trioxide (ATO) is an inorganic arsenical that poses significant environmental and public health risks due to its toxic nature. While it is widely used in various industrial and medicinal applications, the potential harm caused by intentional or accidental exposure cannot be overlooked.
Comparative In Vitro Toxicity of ENDS Aerosols: Impact on Macrophages

As the popularity of electronic nicotine delivery system (ENDS) devices continues to rise, there is a growing need to understand their potential health effects, particularly on immune cells.
MCEMP1: Unraveling the Role of a Lung-Specific Protein in Mast Cell Proliferation and Asthma

Mast cells are crucial players in the body’s defense mechanisms, orchestrating immune responses and contributing to the maintenance of homeostasis. However, when mast cells undergo excessive proliferation or activation, it can lead to chronic inflammatory disorders such as asthma.
Nebulised Mesenchymal Stem Cell-Derived Extracellular Vesicles

Mesenchymal stem cells (MSCs) have shown great promise in cell therapy for various diseases, including lung injury. However, recent research has focused on the therapeutic potential of extracellular vesicles (EVs) derived from MSCs.
Respiration & Neural Dynamics in Odor Fear Learning

The ability to time intervals is critical for fundamental animal behaviors such as anticipating rewarding or aversive events. However, the neurobiological basis of interval timing in Pavlovian associative learning is poorly understood.
Clinical Significance of Animal Models for Inhaled Pharmaceuticals and Biopharmaceuticals

Lung function testing is often considered of prime importance in preclinical respiratory research. Being integrative, functional, and translational, the conclusions of such assessments typically impact the decision-making process.
Pulmonary Impacts of Exercise in Polluted Environments

Exercising outdoors, particularly when done at high intensity and in polluted environments, could cause molecular alterations that could impact pulmonary function.
Strategic Assessment of Lung Function

Lung function testing is often considered of prime importance in preclinical respiratory research. Being integrative, functional, and translational, the conclusions of such assessments typically impact the decision-making process.
Exploring ALI Exposures: From Cell Lines to Endpoints

Traditional submerged cell culture techniques have well-known limitations for aerosol exposure studies; for instance, the impact of exposure dilution within the media and the poor solubility/sedimentation of some exposure particles1. Air liquid interface (ALI) cultures are a technique whereby cells are grown on a microporous membrane insert, immersed in a media-containing well.
Airway Hyperreactivity in Chlorine Exposed EIB Swimmers Model

Airway hyperresponsiveness (AHR) and exercise-induced bronchoconstriction (EIB) are conditions commonly affecting high-intensity athletes such as competitive swimmers.AHR and EIB in athletes have been well defined, however, studies focusing on immunological relevance in symptom onset may prove useful in developing preventative measures.