APS Summit 2026 Hosted Session
Session Description: In this workshop, Dr. Levitt explores how opioids like fentanyl disrupt serotonin pathways that support breathing. She will present new findings showing how targeting specific serotonin neurons and 5HT2C receptors may offer a promising strategy to counter opioid‑induced respiratory depression, complementing existing overdose treatments.
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Speaker Spotlight:
Dr Erica S Levitt – University of Michigan
Biography: Dr Levitt holds a PharmD from Ohio Northern University and a PhD in Pharmacology from the University of Michigan, followed by postdoctoral training at the Vollum Institute. Her lab investigates the mechanisms behind opioid‑induced respiratory depression and breathing abnormalities using advanced cellular and systems‑level approaches.
Combining Telemetry & Plethysmography
Combining implantable telemetry with whole body plethysmography offers a powerful approach that provides researchers with an in-depth understanding of complex mechanisms that link respiratory, cardiovascular and neurological functions.
The integration of these solutions on a synchronized platform, for concurrent analysis of cardiovascular, respiratory, neurological, video and audio data (vocalizations, cough) is relevant for the study of various diseases and conditions.
- Neurologic and muscular disorders (Duchenne muscular dystrophy, Amyotrophic Lateral Sclerosis, Pompe disease etc.)
- Sleep-Related Breathing Disorders
- Behavioral studies
- Study of the central and peripheral chemoreflex response
In Vivo and In Vitro Smoke Exposure
We are proud to introduce our new expoCube, adding robust in vitro exposure to the automated inExpose system.
The expoCube provides a novel ALI (air liquid interface) culture exposure system, integrating with the inExpose’s existing exposure generators such as the integrated cigarette smoking robot and industry leading e-cigarette extensions.
The expoCube features:
- Reproducibility: Efficient, uniform, and precise exposure of particulates onto target cells and tissues.
- Precision: Optimized flow paths using advanced computational fluid dynamics (CFD) modelling.
- Deposition: Patented thermophoresis, increasing the deposition efficiency of small particles without imparting unnatural electrostatic charges onto the aerosols.
in vivo Respiratory Mechanics Measurements
The flexiVent lung function solution is widely regarded as the gold standard for in vivo respiratory mechanics measurements. It goes beyond traditional resistance and compliance mechanics of pulmonary ventilation, and captures crucial details about the mechanical properties of conducting airways, terminal airways and parenchyma.
The flexiVent achieves the highest sensitivity and reproducibility by precisely controlling experimental conditions.
