Rare and orphan lung diseases are those that affect fewer than one in 2,000 people and up to 80% of these diseases are caused by genetic factors. There are over 6,000 such disorders, many of which are also Orphan diseases; those diseases that may be of limited interest to medical or scientific communities, with limited treatment and/or ongoing development.
As many rare diseases are heavily influenced by genetic background, the development of animal models which recapitulate the disease phenotype can be a major development hurdle for the study of rare diseases.
Measuring lung physiology of novel models to properly characterize phenotypes of rare and orphan lung diseases is vital during new strain development. As these differences may appear transiently or with easily missed hallmarks, it is imperative to use an extremely sensitive system to quantify the data.
The flexiVent facilitates highly sensitive and reproducible phenotype characterization to delineate the difference between even minor differences in disease presentation with very small subject groups. Detailed respiratory mechanics measurements and the option to configure experimental conditions allows researchers to reduce the time required for development and subsequent studies using novel strains, saving both time and resources.
Save time evaluating SCIREQ equipment by having a SCIREQ Application Specialist conduct a custom
literature research. Researchers will receive an email report showing SCIREQ publications relevant to their specific application research area, along with custom equipment recommendations and commentary.
