The 2026 Society of Toxicology (SOT) Conference Exhibition will take place in San Diego from March 23rd to the 25th.
Come meet us at Booth 1605 & 1607 !
Date and time: Wednesday March 25th at 12:15-1:15 pm PST.
Location: San Diego Convention Center Room 23C
General Session Description: This session explores how aerosolized toxins and particulate matter impact the human respiratory system by integrating environmental exposure science with mechanistic pathology. Using in vitro human airway models at the air–liquid interface and in vivo humanized mouse inhalation models, presenters examine pathways driving pro-inflammatory signaling and allergic sensitization to cyanotoxins and mineral-rich dust. Together, these approaches improve prediction of human susceptibility and support the development of targeted interventions for emerging environmental threats.
The expoCube is an Air Liquid Interface (ALI)/Transwell in vitro / ex vivo exposure system that efficiently deposits aerosols onto cells and tissues. When combined with SCIREQ’s inExpose® inhalation exposure platform, the expoCube allows researchers to integrate in vitro, ex vivo and in vivo models, optimizing compound usage while adhering to the 3Rs principle.
The expoCube features:
vivoFlow+ plethysmograph allows studying pulmonary function in conscious, spontaneously breathing laboratory subjects.
The standard barometric plethysmography technique measures flow and pressure changes that occur while the subject is breathing, before and after exposure to a drug or other challenges.
