EN | FR
EN | FR
Search

MBML 2026 Annual Retreat

The  2026 Molecular Biology and Medicine of the Lung Annual Meeting took place from June 24th to the 26th at the Rauischholzhausen Castle

Keynote Speaker

John Morse – Global Sales Director

 Talk Title: Making Lung Models Matter: Tools to Integrate In Vitro and In Vivo Physiology

Lung disease research spans molecular signaling, cellular responses, tissue remodeling, whole-organ physiology, and exposure biology, yet these levels are often studied in isolation, limiting translation to the clinic.

This session explored how integrating in vitro, ex vivo, and in vivo physiology can strengthen the relevance and translational value of lung research models by connecting molecular findings with functional outcomes.

Download Presentation Summary:

Featured Products

vivoFlow+ plethysmograph

vivoFlow+ plethysmograph allows studying pulmonary function in conscious, spontaneously breathing laboratory subjects.

The standard barometric plethysmography technique measures flow and pressure changes that occur while the subject is breathing, before and after exposure to a drug or other challenges.

New Research Platform for Precision Cut Lung Slices

Precision-Cut Lung Slices (PCLS) help researchers understand pathophysiological mechanisms associated with various respiratory diseases. The physioLens is a scientific platform that provides accurate physiological and image-based outcomes in a reproducible fashion. It includes an automated microscope and fluid handling system. The physioLens features:
  • Automation: The physioLens is capable of capturing images anywhere on slices in a 6 well plate and apply doses without user intervention. Images are analyzed in real-time to provide bronchoconstriction data. 
  • Dosing: Agonists are provided to the slice without user intervention by a dosing nozzle, that can provide a 95% media exchange in less than 20 seconds. In addition, eight dosing bottles are provided to complete a detailed dose response automatically.
  • Image analysis: Images of airways are automatically processed to capture the lumen contours and then calculate bronchoconstriction. 
  • Slice Scanning: Navigating a slice is not necessary with our airway configuration wizard complete with full slice mapping. Fine tune the positions of interest with our click-and-drag XY navigation.

in vivo Respiratory Mechanics Measurements

The flexiVent lung function solution is widely regarded as the gold standard for in vivo respiratory mechanics measurements. It goes beyond traditional resistance and compliance mechanics of pulmonary ventilation, and captures crucial details about the mechanical properties of conducting airways, terminal airways and parenchyma.

The flexiVent achieves the highest sensitivity and reproducibility by precisely controlling experimental conditions.

Contact SCIREQ for further information