The physioLens solution features Automation, Dosing, Image Analysis, Cilia Beating Frequency and Slice Scanning.
The physioLens is capable of capturing images anywhere on slices in a 6 well plate and apply doses without user intervention. Images are analyzed in real-time to provide bronchoconstriction data.
Agonists are provided to the slice without user intervention by a dosing nozzle, that can provide a 95% media exchange in less than 20 seconds. In addition, eight dosing bottles are provided to complete a detailed dose response automatically.
The physioLens accurately measures cilia beating frequency within the physioWare software. It provides results as frequency maps and averages, aligning well with known values from published literature. The system is optimized to measure frequencies up to 25 beats per second, with the potential for even higher measurements at faster recording speeds.
Images of airways are automatically processed to capture the lumen contours and then calculate bronchoconstriction.
Navigating a slice is not necessary with our airway configuration wizard complete with full slice mapping. Fine tune the positions of interest with our click-and-drag XY navigation.
Tissue slices are held in place with a transparent when wet membrane allowing seamless sample-mounting.
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