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1. EXPERIMENTAL GOAL The forced oscillation technique (FOT) using the flexiVent has been the gold standard for pulmonary function tests (PFTs) in small animal in vivo studies for many years2,3. [...]

Cannabis is one of the most popular recreational drugs used worldwide. Since the recent legalization of marijuana across several countries and states, there is an increased interest in research [...]

Kumar et al. (2020) recently published a novel manuscript that combined work on cellular and mouse models shows that hyperglycemic conditions and the resultant metabolic alterations cause DNA [...]

New insights from AITox 2020! The  AITox seminars this year were quite interesting and informative, the organizers did a great job pivoting into the virtual world! If you missed the opportunity [...]

In cigarette and e-cigarette studies, the initial composition of the compound being aerosolized, as well as puffing topography has appreciable effects on the puff characteristics and downstream [...]

Since COVID-19 was declared a global pandemic in March 2020, a massive wave of mobilization has been seen from various companies and organizations at different fronts, to not only help fight the [...]

COVID-19 has rapidly spread throughout the world and was declared a pandemic in March of 2020. Currently, there is no clinically validated treatment or vaccine for COVID-19. However, studies have [...]

Relative to traditional cigarettes, E-cigarette use is increasing due to the widespread perception of e-cigarettes being a healthier alternative. More recently, concern about e-cigarette use is [...]

New insights from pressure-volume loops Lung function measurements with the flexiVent frequently include Pressure-Volume (PV) loops for insight on the intrinsic elastic properties of the [...]

Chronic lung diseases (CLDs) such as COPD, emphysema, interstitial lung fibrosis impair airflow, alter lung elastance, and impact pulmonary vascular hemodynamics which could result in ventricle [...]