Advanced Lung Function Measurement In A Novel HIV/TB Co-infection in Mouse Models
Tuberculosis and Human Immunodeficiency Virus are major global health threats. Their interaction worsens disease severity, as HIV reduces CD4+ T cells, making individuals more vulnerable to TB.
Advancing TB Treatment: Role of flexiVent in Evaluating Bacteriophage Therapy
A recent study by Yang, F., et al (2024) has explored the potential of bacteriophage therapy for treating multi-drug resistant Mycobacterium tuberculosis (Mtb) infections
Studying Flow-Induced Pulmonary Hypertension and Compensatory Lung Growth
In the realm of pulmonary research, the search to understand complex lung conditions has led to the development of various animal models.
The Potential Of WNT/Β-Catenin Modulation in Treating Pulmonary Fibrosis
Pulmonary fibrosis, particularly idiopathic pulmonary fibrosis (IPF), represents a significant challenge in healthcare due to its detrimental impact on lung function and limited treatment options.
NEBS and PIEZO2: Guardians of The Respiratory Galaxy
In a recent Nature publication by Schappe,M (2024), researchers have revealed a fascinating aspect of respiratory physiology: the role of sensory neurons in guarding against airway obstruction and orchestrating crucial reflexes to maintain respiratory function.
Choosing the Right Mouse Strain for Respiratory Disease Modeling: A Critical Consideration
Discover why choosing the right mouse strain (C57BL/6 vs. BALB/c) is critical for respiratory disease modeling. Learn how baseline lung mechanics and tissue stiffness impact preclinical research.
FEV Measurements in Preclinical Models of Respiratory Disease
As researchers strive to bridge the gap between preclinical investigations and clinical outcomes, the accurate assessment of Forced Expired Volume (FEV) and Forced Vital Capacity (FVC) emerges as a cornerstone for establishing translational relevance.
Understanding the Pulmonary Effects of Inhaled Arsenic Trioxide (ATO)
Arsenic trioxide (ATO) is an inorganic arsenical that poses significant environmental and public health risks due to its toxic nature. While it is widely used in various industrial and medicinal applications, the potential harm caused by intentional or accidental exposure cannot be overlooked.
MCEMP1: Unraveling the Role of a Lung-Specific Protein in Mast Cell Proliferation and Asthma
Mast cells are crucial players in the body’s defense mechanisms, orchestrating immune responses and contributing to the maintenance of homeostasis. However, when mast cells undergo excessive proliferation or activation, it can lead to chronic inflammatory disorders such as asthma.
Nebulised Mesenchymal Stem Cell-Derived Extracellular Vesicles
Mesenchymal stem cells (MSCs) have shown great promise in cell therapy for various diseases, including lung injury. However, recent research has focused on the therapeutic potential of extracellular vesicles (EVs) derived from MSCs.