2024 ATS - American Thoracic Society

 The 2024 American Thoracic Society (ATS) Conference will take place in San Diego, California at the San Diego Convention Center from May 17th to the 22nd.   Come meet us at Booth 1535 !   

Annual Hosted Session: Precision-Cut Lungs Slices as Translational Models of Airway Reactivity

SCIREQ will be hosting a free in-person session on May 21st, 2024 from 4-5 PM PST. The event will be held at the Hilton San Diego Bayfront in Room Aqua 300. Space is limited, so please register to ensure your seat !

Our team is available for meetings during the conference from Friday the 17th to Wednesday the 22nd from 9 am – 4:30 pm PST

Schedule a meeting with us using the links below

David Brunet
President & CEO

John Morse
Sales Manager

Isabelle Aiken
Application Specialist

Fatima Moukhariq
Application Specialist

New Research Platform for Precision Cut Lung Slices

Precision-Cut Lung Slices (PCLS) help researchers understand pathophysiological mechanisms associated with various respiratory diseases. The physioLens is a scientific platform that provides accurate physiological and image-based outcomes in a reproducible fashion. It includes an automated microscope and fluid handling system.

The physioLens features:

  • Automation: The physioLens is capable of capturing images anywhere on slices in a 6 well plate and apply doses without user intervention. Images are analyzed in real-time to provide bronchoconstriction data. 
  • Dosing: Agonists are provided to the slice without user intervention by a dosing nozzle, that can provide a 95% media exchange in less than 20 seconds. In addition, eight dosing bottles are provided to complete a detailed dose response automatically.
  • Image analysis: Images of airways are automatically processed to capture the lumen contours and then calculate bronchoconstriction. 
  • Slice Scanning: Patented thermophoresis, increasing the deposition efficiency of small particles without imparting unnatural electrostatic charges onto the aerosols.

In Vivo and In Vitro Smoke Exposure

We are proud to introduce our new expoCube, adding robust in vitro exposure to the automated inExpose system.

The expoCube provides a novel ALI (air liquid interface) culture exposure system, integrating with the inExpose’s existing exposure generators such as the integrated cigarette smoking robot and industry leading e-cigarette extensions.

The expoCube features:

  • Reproducibility: Efficient, uniform, and precise exposure of particulates onto target cells and tissues.
  • Precision: Optimized flow paths using advanced computational fluid dynamics (CFD) modelling.
  • Deposition: Patented thermophoresis, increasing the deposition efficiency of small particles without imparting unnatural electrostatic charges onto the aerosols.