Ventilator-Assisted Aerosol Delivery (VAAD)

VAAD is a new innovative technique using the flexiVent, introduced to improve in vivo aerosol administrations for drug delivery and disease modelling. The VAAD approach minimizes subject-to-subject variability, and fosters a highly homogenous aerosol deposition within the lung. This optimized aerosol protocol is synced with mechanical ventilation to standardize features of the subject’s breathing pattern and to measure lung function prior to and post administration.

This document covers:

  • VAAD homogenous deposition patterns
  • VAAD for disease modeling
  • VAAD for drug delivery