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What is compliance?

Compliance is a classic parameter used to describe the mechanical properties of the respiratory system. It provides a quantitative assessment of the distensibility or elastic properties of the respiratory system. It can be influenced by a variety of structural and physiological variables, including age, lung volume, muscular tension, surfactant properties, oedema, inflammation, disease status, or breathing frequency. Its value generally increases under conditions of reduced recoil (e.g. emphysema) and decreases as stiffness develops (e.g. fibrosis). Due to this inverse relationship, the reciprocal parameter Elastance (E=1/C) is more commonly used in preclinical respiratory research.

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