In Applications, flexiVent, inExpose, vivoFlow

Smoking has reached an epidemic proportion
worldwide and its effect in terms of health-related issues is huge. While
smoking prevention and cessation are key to bringing an end to this epidemic,
scientific research is needed both to understand smoke-induced
pathophysiological mechanisms and to develop novel therapeutic agents to treat
patients. The smoking market is also changing, as seen with the introduction of
new nicotine delivery devices, such as electronic cigarettes. Their rapid
adoption has raised a lot of questions relating to the safety and benefits of
these devices, most of which remain incompletely addressed at the present day.


Given the extended time period needed to
generate sound scientific evidence, research on tobacco or tobacco-related
products requires a joint effort. SCIREQ is proud to be part of these efforts by
offering state-of-the-art equipment for basic in vivo and in vitro studies.
Particularly well adapted to generate consistent and reproducible exposure
environments is the inExpose system, a versatile and programmable exposure
system that can be configured with several smoke and vape generating devices. The
impact on the respiratory system can then be assessed using invasive and
non-invasive lung function measurement techniques. Sitting at the forefront,
the flexiVent system offers a variety of lung function measurements to address
specific questions or gain novel insights. These accurate and detailed measurements
can be complemented by the non-invasive barometric monitoring of the ventilation
profile or disease symptoms (e.g. cough) throughout a study, which can involve
repeated exposure sessions over several months. Finally, any direct effect on
either airway or vascular smooth muscle can also be evaluated in absence of
external influences using tissue baths for an overall meaningful and far-reaching
Please contact us to find out more or visit our website at
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