tremoFlo P-100

The tremoFlo P-100 Airway Oscillometry System (AOS) is a portable lung function testing instrument that can measure respiratory mechanics in large animals (dogs, NHPs) non-invasively. The system comprises a lightweight handheld device attached to a cradle unit. Subjects breathe directly into the handheld unit during measurements via a disposable anti-bacterial/viral filter and a subject mask. The tremoFlo software provides subject management, testing and result interpretation capabilities.

Using the Forced Oscillation Technique (FOT), quickly capture detailed information about the respiratory system with the simple push of a button!


  • Respiratory assessment for safety and toxicology studies using dogs and NHP models
  • Demonstrating compliance with ICH guidelines
  • Studying the off-target effects
  • Integrating safety endpoints to existing toxicology studies
  • Drug efficacy and validation studies
  • Exploratory toxicology, cross-reactivity studies, and more!

Techniques & Measurements

Airwave Oscillometry is a novel method for measuring lung function using the most advanced form of the Forced Oscillation Technique (FOT). The tremoFlo P-100 accurately measures lung function by superimposing a gentle multi-frequency airwave onto the subject’s respiratory airflow. Throughout the AOS measurement, the subject just breathes normally.

Here is a list of outcomes paramters measured by the tremoFlo software:

R5: Low-frequency Resistance (5 Hz), reflects overall lung resistance.

R19: Mid-frequency Resistance (19 Hz), reflects mostly conducting airways.

X5: Low-frequency Reactance (5 Hz), reflects compliance& small airways.

Fres: Resonance frequency, increases in small airway disease.

VT: Tidal volume, determines the normal volume of air being displaced.

RR: Respiratory rate, measures the number of breaths per minute.



Dimensions (WxDxH)
Handheld on cradle

8.3 x 5.5 x 9.4 in
Handheld & cradle
3.7 lbs


Computer System Requirements

Type Desktop, All-in-One, Laptop or Tablet
Operating System Windows 7/8/8.1, 32 or 64-bit
CPU Dual-core 1.6 GHz or more
Memory Min. 500 GB HDD, 3 GB RAM
Screen Resolution 1280 x 800
Connectivity RC-45 Ethernet or USB-to-Ethernet, Wireless where permitted


tremoFlo P-100