Control of Breathing
Respiration functions through a complex network of neural controls and feedback mechanisms as the body constantly adjusts its breathing rate and tidal volume to meet respiratory metabolic demands.
Several diseases and conditions disrupt the neurological and muscular signals, compromising the body’s ability to breathe normally. Neurologic and muscular disorders like Duchenne muscular dystrophy, amyotrophic lateral sclerosis (ALS), Pompe disease, and sleep-related breathing disorders (SRBD) are key examples of neuromotor impairment that can lead to respiratory insufficiency.
Control of breathing requires complex interactions between the brain, nerves, muscles and lungs, which should be studied simultaneously to gain a deep understanding of breathing behavior.